EPO doping can boost the number of red blood cells and there by increased availability of oxygen to the muscles. This can help the athlete with increased performance ability and endurance. Blood doping is illegal especially in professional sports. Professional athletes are asked to take this test to find out if they are violating the anti-doping law. About Contact Events News. Search Search. You and Your Hormones. Students Teachers Patients Browse.
Human body. Home Hormones Erythropoietin. Erythropoietin Erythropoietin is a hormone, produced mainly in the kidneys, which stimulates the production and maintenance of red blood cells. Alternative names for erythropoietin Erythropoietin is commonly referred to as EPO.
In three patients with renal adenocarcinomas associated with polycythemia, in situ hybridization showed a strong labeling of the tumor cells. Epo secretion is stimulated by hypoxia, which is detected by an oxygen sensor located in the kidney. This oxygen sensor has been recently shown to be an heme protein. When the kidneys are damaged, their ability to produce erythropoietin is compromised and anemia ensues.
The anemia associated with chronic kidney disease can be alleviated by treatment with erythropoietin. Such treatment is also valuable in a number of other types of disease associated with deficits in red blood cells production. Other Endocrine Tissues and Hormones. Updated Send comments to Richard. Bowen colostate. However, adding more erythropoietin to a healthy body can be dangerous and increase the risk of side effects.
ESA injections can help treat a number of conditions, but they do have the potential for side effects and risks. Healthy people who abuse ESA injections may be more at risk of these side effects, as the unnecessary increase of red blood cells may make the blood thicker and more prone to clotting. In some cases of use among people with cancer, the ESA may cause the tumor to grow. Therefore, these people may only receive ESAs for a short time to help prevent the symptoms of chemotherapy.
Abnormal erythropoietin levels may indicate an issue in the kidneys or bone marrow. Tests for erythropoietin levels can help doctors identify the underlying cause of blood conditions. Such causes include anemia. In people with low erythropoietin levels due to kidney disease or other conditions, ESA injections may help treat the issue.
ESA injections carry some risks, however, as they make the blood thicker and more prone to clotting. Also, healthy people who abuse these injections may be at a higher risk of more serious complications. Anyone who is uncertain about their diagnosis or treatment should talk to their doctor about all the treatment options before making any changes.
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The body does not have enough red blood cells and is unable to deliver enough oxygen around the body. Bone marrow is a soft, gelatinous tissue inside some bones.
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